Arthritis Baricitinib Covid – From the very first day, when coronavirus was just spreading in China alone, scientists were looking to find a cure for the virus. Even though they have not been successful 100% even after 2 ½ years, they are still doing everything to help mankind.
First of all, in several studies, one medicine named hydroxychloroquine was found to be very effective on the symptoms of coronavirus. After a few weeks, that myth was broken when the medicine was not able to replicate the results.
After that, scientists and experts tried many ways to contain the spread of the virus, for example, lockdown, social distancing, use of masks, regular testing, and vaccination.
Till now, the world is only following four things, social distancing, use of masks, vaccination, and regular testing. But, recently, one study concluded and made the news that Baricitinib A medicine used to treat Rheumatoid Arthritis (RA) can help and save critical COVID patients.
What is Baricitinib?
Baricitinib Is an oral drug that dampens an overactive immune system. The drug is mostly given to people who have conditions like Rheumatoid Arthritis (RA).
in recent studies and papers published by World Health Organization, it was clear that in many studies, Baricitinib has clearly shown many benefits and helped people suffering from severe COVID infection
The drug has also been authorized by the United States Food and Drug Administration to use on severe COVID infected patients in combination with remdesvir.
How does Baricitinib help to recover COVID patients
Even though Baricitinib is only used to treat patients with Rheumatoid Arthritis (RA), In July 2021, the Food and Drug Administration of the United States gave emergency use authorization to treat covered patients with severe and critical symptoms.
The emergency use authorization for Baricitinib Came after the World Health Organization stated the use of medicine to treat critical patients.
As per the notification issued by the Food and Drug administration, Baricitinib can be used alone to treat COVID-19 patients in hospitals aged two and older. In the notification, Food and drug administration also wrote that it is only required for patients who are on supplemental oxygen, non-invasive or invasive mechanical ventilation, or extracorporeal membrane oxygenation.
Previously, doctors had to use Baricitinib in combination with remdesvir, But now doctors can recommend using it without in combination with any other medicine.
A study was conducted in 18 hospitals in the United States, including Grady Memorial Hospital and the Atlanta VA, in association with hospitals in Argentina, Brazil, and Mexico from December 2020 to April 2021.
There were more than 1500 patients included in the study with severe symptoms of COVID in 19, and it also included the study of placebo. After 60 days, more than 60% of patients given a placebo had died versus only 45% of those receiving the medicine.
Side Effects of Baricitinib
Good things aside, Baricitinib comes with several side effects associated with it. You might catch one or more serious side effects at the same time due to the use of Baricitinib.
Don’t worry, and doctors do not suggest this drug to everyone because doctors only suggest it when the benefit to you is greater than the risk of side effects.
But you must keep on entering your symptoms if you are not with your doctor while taking medicine.
Baricitinib Is known to cause anemia in several cases. Once you start having anemia, your skin will get a bit paler than normal, and you usually feel tired all the time. Apart from that, your heart might also beat faster than normal.
As per the experts, if you feel any symptoms related to anemia, you should contact your doctor as soon as possible because it may cause life-threatening conditions.
In many cases, after taking Baricitinib, people have reported back having some sort of liver disease. If after taking medicine, you are having a constant feeling of nausea and vomiting which won’t go away even after some time, loss of appetite, and stomach pain at the same time, you should let your health provider know about it.
Apart from that, you might also get yellow eyes and skin, including dark urine. These all are Symptoms of having serious liver diseases. Kindly do not ignore any of them.
Serious Allergic Reactions
As we have already talked about, Baricitinib Can lower your ability to fight some serious infections. As for the experts, you should seek medical help right away if you are having any kind of allergic reaction, including rash, itching, swelling in the tongue or face, along with dizziness.
The above-given side effects are not a complete list of side effects you can get after taking medicine. You should contact your doctor or pharmacist first before you take the medicine and discuss your possible side effects.
Doctors usually don’t recommend it to everyone. So kindly keep in mind if your doctor has advised you to take this medicine, this means the risk of taking the medicine is not as big as its benefits.
Apart from that kindly do not stop taking your medicine suddenly, you should contact your doctor first and then as per the instructions you can decide.
Warnings Related to Baricitinib
Even though doctors have been using Baricitinib for a very long time to treat arthritis, recently, Several studies have indicated positive results of using the drug on severe COVID patients.
But still, we cannot eliminate the warnings that come with the medicine. Several warnings are starting from mild to all the way severe. Let’s take a look at a few of them.
On the box, it is written, Baricitinib may lower your ability to fight infections, and you might get a serious infection or make any infection serious you already have.
Pneumonia, shingles, and urinary tract infections are some of the most common And serious infections due to compromised ability to fight infections.
If you are taking medicine, you should let your doctor know about any infection, either mild or severe, including sore throat, fever, chills, cough, painful urination, etc.
In serious problems, you might also develop several types of cancer, including skin and lung cancer, due to the use of this medication.
Apart from that, you might also lose weight and get night sweats. In some rare cases, Baricitinib may also cause blood clots, and it could result in stroke or heart attack. You should keep track of your health before and after taking the medication.
In case you get any new diseases, including dizziness, fainting, unusual sweating, pain in the groin, severe headaches, or trouble sleeping, you should let your doctor know as soon as possible you might require emergency medical assistance. [Source]
Every day scientists and experts are conducting new studies on COVID-19 and gathering information on how to save severe patients. Even though coronavirus might not be as deadly as you think, it may cause serious life-threatening conditions in some people.
Recently, after a study was published on the good effects of Baricitinib on people with severe COVID conditions, the World Health Organization also approved the study and gave its nod to use the medicine on people with severe COVID infection.
The medicine was able to help and save 20% more people than any other treatment combination. As a result, the United States Food and Drug administration also gave emergency use approval.
Even though Previously, doctors had to use Baricitinib in combination with remdesvir. But, now doctors can recommend it without any other medicine.
Apart from the good things, Baricitinib can also cause serious side effects, and the medicine also comes with a boxed warning. One of the serious side effects, the drug can also cause you to develop several types of cancer, including lung and skin.
What does WHO say about the use of Baricitinib?
The World Health Organization has also approved the use of Baricitinib to treat patients with severe COVID-19 symptoms. WHO stated on the 14th of January 2022 regarding the use of Baricitinib. In the statement, the World Health Organization stressed the world severely or critically more than anything else. It tells everyone to use the medicine only if the patient is in a death or life situation.
Is there any other new development like the findings of Baricitinib?
In a recent statement issued by the World Health Organization, they have found two new drugs for COVID-19. These drugs are not 100% effective, but in the early stage drugs, I’ve been providing significant results against so we’re cases of novel coronavirus. Apart from the famous Baricitinib, the World Health Organization also recommends Sotrovimab to treat COVID patients with Mild symptoms.